Bayer OASIS Study

The Heat is On: Rethinking Menopause Relief

For millions of women, menopause doesn't just quietly arrive—it announces itself. It's the sudden, unpredictable wave of heat surging through your chest in the middle of a meeting. It's the flushed face at dinner. It's the frantic search for a fan, a cold drink, an open window. Hot flashes (or vasomotor symptoms, in clinical terms) are arguably the most notorious hallmark of the menopausal transition, and for far too long, the solutions have felt limited to hormone therapies that aren't right, or safe, for everyone.

But what if relief didn't require hormones at all?

MomDoc Women's Health Research is participating in the Bayer OASIS clinical trial, a pivotal Phase 3 study investigating Elinzanetant—a promising new approach to turning down the heat over a 26-week evaluation period.

The Science of "Alternative" Relief

Rather than replacing lost hormones, this new class of medication targets the brain's temperature control center. According to the official study protocol, this novel development specifically intercepts the signals that cause the flushing:

"The study treatment, elinzanetant, was developed to treat symptoms caused by hormonal changes. It works by blocking a protein called neurokinin from sending signals to other parts of the body, which is thought to play a role in starting hot flashes."

In this double-blind, randomized, placebo-controlled study, participants takes two capsules daily, recording their experiences in an electronic diary to measure both the frequency and severity of hot flashes.

Who Can Participate?

Medical progress relies on the women bold enough to step forward. We are currently enrolling postmenopausal women (ages 40-65) who meet the following key criteria:

• You have experienced at least 12 months of spontaneous amenorrhea (no periods).
• You experience moderate to severe hot flashes and are actively seeking treatment.
• You have not had a hormone-sensitive malignancy (such as breast cancer) or unresolved uterine bleeding.

Participation in MomDoc clinical trials is always voluntary, always free, and often includes compensation for time and travel.

Read the full study details on ClinicalTrials.gov